Antiendothelial cell antibodies and cytotoxicity against endothelial cell in various vasculitis of childhood.
نویسندگان
چکیده
منابع مشابه
Determination the Role of Endothelial Cell-Specific Molecule-1(ESM-1) in Childhood Bronchial Asthma
Background Endothelial Cell-Specific Molecule-1 (ESM-1) is a 50 kDa soluble proteoglycan that is produced mainly the vascular endothelial cells of the kidney and lung. It is produced by the effects of proangiogenic and pro-inflammatory cytokines, and it indicates activation and dysfunction of the vascular endothelium. We aimed to detect the role of ESM-1 in childre...
متن کاملPreparation, characterization and in vitro cytotoxicity evaluation of docetaxel nanoparticles against A549 cell line
Introduction: Docetaxel (DTX) is one of the most potent anticancer drugs in the taxane family. The commercial formulation of DTX for clinical use consists of high concentrations of tween80, which has been caused serious patient`s difficulties. Therefore, preparation of novel drug delivery system with ability of removing tween 80 and targeting on cancer tissue can lead more effective and also de...
متن کاملEvaluation of the Endothelial Cell Antibodies in Serum and Perilymphatic Fluid of Cochlear Implanted Children with Sensorineural Hearing Loss
Introduction: Serum Anti endothelial Cell Antibodies (AECAs) play a prominent role in idiopathic Sensorineural Hearing Loss (SNHL) in that they induce vascular damage (immune mediated).The of the current study is To compare AECAs in serum and perilymphatic .uid of idiopathic SNHL children (<15y) undergoing cochlear implant surgery.Methods: This was a cross sectional study performed in the coch...
متن کاملComparison of cell-ELISA, flow cytometry and Western blotting for the detection of antiendothelial cell antibodies.
OBJECTIVE There is still great uncertainty in the detection of antiendothelial cell antibodies (AECA). The aim of our study was to compare the results obtained using different methods. METHODS Sera were obtained from 71 patients with a variety of vasculitides. Three assay methods were used: cell ELISA, flow cytometry (FACS) and Western blot (WB). RESULTS In the ELISA 12/17 patients with sys...
متن کاملHyperthermia Increases Natural Killer Cell Cytotoxicity against SW-872 Liposarcoma Cell Line
Background: Although there is convincing data in support of the effectiveness of hyperthermia in tumor therapy, the molecular mechanisms underlying the clinical effects of hyperthermia are still poorly understood. Objective: To investigate natural killer (NK) cell cytotoxicity against heat-treated SW-872 and HeLa tumor cell lines. Methods: NKG2D ligands and HLA class I transcription were examin...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nihon Shoni Jinzobyo Gakkai Zasshi
سال: 1995
ISSN: 1881-3933,0915-2245
DOI: 10.3165/jjpn.8.145